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PALB2 mutations in BRCA1/2-mutation negative breast and ovarian cancer patients from Poland
BACKGROUND: The PALB2 gene encodes a protein that plays a crucial role in maintaining genomic integrity. Germline inactivating mutations in PALB2 are associated with an increased risk of breast and ovarian cancer. The prevalence and spectrum of recurrent PALB2 germline mutations in breast and ovaria...
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| 出版年: | BMC Med Genomics |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5345197/ https://ncbi.nlm.nih.gov/pubmed/28279176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12920-017-0251-8 |
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