Treating triple negative breast cancer cells with erlotinib plus a select antioxidant overcomes drug resistance by targeting cancer cell heterogeneity

Among breast cancer patients, those diagnosed with the triple-negative breast cancer (TNBC) subtype have the worst prog-nosis. TNBC does not express estrogen receptor-alpha, progesterone receptor, or the HER2 oncogene; therefore, TNBC lacks targets for molecularly-guided therapies. The concept that...

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Pubblicato in:Sci Rep
Autori principali: Bao, Bin, Mitrea, Cristina, Wijesinghe, Priyanga, Marchetti, Luca, Girsch, Emily, Farr, Rebecca L., Boerner, Julie L, Mohammad, Ramzi, Dyson, Greg, Terlecky, Stanley R., Bollig-Fischer, Aliccia
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345072/
https://ncbi.nlm.nih.gov/pubmed/28281569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44125
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