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Longitudinal changes of cerebral glutathione (GSH) levels associated with the clinical course of disease progression in patients with secondary progressive multiple sclerosis

BACKGROUND: Increased oxidative stress leads to loss of glutathione (GSH). We have reported lower cerebral GSH in patients with secondary progressive multiple sclerosis (SPMS), indicating the involvement of oxidative stress in MS pathophysiology. OBJECTIVE: This study expanded upon our earlier work...

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Publicat a:Mult Scler
Autors principals: Choi, In-Young, Lee, Phil, Hughes, Abbey J., Denney, Douglas R., Lynch, Sharon G.
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344731/
https://ncbi.nlm.nih.gov/pubmed/27620894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458516669441
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