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Longitudinal changes of cerebral glutathione (GSH) levels associated with the clinical course of disease progression in patients with secondary progressive multiple sclerosis

BACKGROUND: Increased oxidative stress leads to loss of glutathione (GSH). We have reported lower cerebral GSH in patients with secondary progressive multiple sclerosis (SPMS), indicating the involvement of oxidative stress in MS pathophysiology. OBJECTIVE: This study expanded upon our earlier work...

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Detalhes bibliográficos
Publicado no:Mult Scler
Main Authors: Choi, In-Young, Lee, Phil, Hughes, Abbey J., Denney, Douglas R., Lynch, Sharon G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344731/
https://ncbi.nlm.nih.gov/pubmed/27620894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1352458516669441
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