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The actin regulator zyxin reinforces airway smooth muscle and accumulates in airways of fatal asthmatics

Bronchospasm induced in non-asthmatic human subjects can be easily reversed by a deep inspiration (DI) whereas bronchospasm that occurs spontaneously in asthmatic subjects cannot. This physiological effect of a DI has been attributed to the manner in which a DI causes airway smooth muscle (ASM) cell...

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Pubblicato in:PLoS One
Autori principali: Rosner, Sonia R., Pascoe, Christopher D., Blankman, Elizabeth, Jensen, Christopher C., Krishnan, Ramaswamy, James, Alan L., Elliot, John G., Green, Francis H., Liu, Jeffrey C., Seow, Chun Y., Park, Jin-Ah, Beckerle, Mary C., Paré, Peter D., Fredberg, Jeffrey J., Smith, Mark A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344679/
https://ncbi.nlm.nih.gov/pubmed/28278518
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0171728
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