Disrupting Actin-Myosin-Actin Connectivity in Airway Smooth Muscle as a Treatment for Asthma?

Breathing is known to functionally antagonize bronchoconstriction caused by airway muscle contraction. During breathing, tidal lung inflation generates force fluctuations that are transmitted to the contracted airway muscle. In vitro, experimental application of force fluctuations to contracted airw...

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Main Authors: Lavoie, Tera L., Dowell, Maria L., Lakser, Oren J., Gerthoffer, William T., Fredberg, Jeffrey J., Seow, Chun Y., Mitchell, Richard W., Solway, Julian
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Thoracic Society 2009
Ábhair:
Thomas L. Petty Aspen Lung Conference: Asthma: Insights and Expectations
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2677405/
https://ncbi.nlm.nih.gov/pubmed/19387033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1513/pats.200808-078RM
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