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MEK modulates force-fluctuation-induced relengthening of canine tracheal smooth muscle

Tidal breathing, and especially deep breathing, is known to antagonise bronchoconstriction caused by airway smooth muscle (ASM) contraction; however, this bronchoprotective effect of breathing is impaired in asthma. Force fluctuations applied to contracted ASM in vitro cause it to relengthen, force-...

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Détails bibliographiques
Auteurs principaux: Dowell, M.L., Lavoie, T.L., Lakser, O.J., Dulin, N.O., Fredberg, J.J., Gerthoffer, W.T., Seow, C.Y., Mitchell, R.W., Solway, J.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3918254/
https://ncbi.nlm.nih.gov/pubmed/20110395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1183/09031936.00160209
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