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A Phase II, Randomized, Double‐Blind, Placebo‐Controlled Study of Simtuzumab in Combination with FOLFIRI for the Second‐Line Treatment of Metastatic KRAS Mutant Colorectal Adenocarcinoma

LESSONS LEARNED. The safety profile in the patient groups who received FOLFIRI and simtuzumab did not differ from that in the FOLFIRI and placebo group. The addition of simtuzumab to chemotherapy with FOLFIRI does not improve clinical outcomes in patients with metastatic KRAS mutant colorectal carci...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Hecht, J. Randolph, Benson, Al B., Vyushkov, Dmitry, Yang, Yingsi, Bendell, Johanna, Verma, Udit
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344646/
https://ncbi.nlm.nih.gov/pubmed/28246207
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0479
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