Pediatric, Adolescent, and Young Adult Thyroid Carcinoma Harbors Frequent and Diverse Targetable Genomic Alterations, Including Kinase Fusions

BACKGROUND. Thyroid carcinoma, which is rare in pediatric patients (age 0–18 years) but more common in adolescent and young adult (AYA) patients (age 15–39 years), carries the potential for morbidity and mortality. METHODS. Hybrid‐capture‐based comprehensive genomic profiling (CGP) was performed pro...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Vanden Borre, Pierre, Schrock, Alexa B., Anderson, Peter M., Morris, John C., Heilmann, Andreas M., Holmes, Oliver, Wang, Kai, Johnson, Adrienne, Waguespack, Steven G., Ou, Sai‐Hong Ignatius, Khan, Saad, Fung, Kar‐Ming, Stephens, Philip J., Erlich, Rachel L., Miller, Vincent A., Ross, Jeffrey S., Ali, Siraj M.
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2017
Assuntos:
Endocrinology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344643/
https://ncbi.nlm.nih.gov/pubmed/28209747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2016-0279
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