EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.
Activated macrophage cytotoxicity is characterized by loss of intracellular iron and inhibition of certain enzymes that have catalytically active nonheme-iron coordinated to sulfur. This phenomenon involves the oxidation of one of the terminal guanidino nitrogen atoms of L-arginine, which results in...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1990
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53443/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153975/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.3.1223 |
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