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EPR demonstration of iron-nitrosyl complex formation by cytotoxic activated macrophages.

Activated macrophage cytotoxicity is characterized by loss of intracellular iron and inhibition of certain enzymes that have catalytically active nonheme-iron coordinated to sulfur. This phenomenon involves the oxidation of one of the terminal guanidino nitrogen atoms of L-arginine, which results in...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Lancaster, J R, Hibbs, J B
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1990
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC53443/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2153975/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.3.1223
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