Direct Lymph Node Vaccination of Lentivector/Prostate-Specific Antigen is Safe and Generates Tissue-Specific Responses in Rhesus Macaques

Anti-cancer immunotherapy is emerging from a nadir and demonstrating tangible benefits to patients. A variety of approaches are now employed. We are invoking antigen (Ag)-specific responses through direct injections of recombinant lentivectors (LVs) that encode sequences for tumor-associated antigen...

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Publicat a:Biomedicines
Autors principals: Au, Bryan C., Lee, Chyan-Jang, Lopez-Perez, Orlay, Foltz, Warren, Felizardo, Tania C., Wang, James C.M., Huang, Ju, Fan, Xin, Madden, Melissa, Goldstein, Alyssa, Jaffray, David A., Moloo, Badru, McCart, J. Andrea, Medin, Jeffrey A.
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5344243/
https://ncbi.nlm.nih.gov/pubmed/28536373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines4010006
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