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Essential Roles of E3 Ubiquitin Ligases in p53 Regulation

The ubiquitination pathway and proteasomal degradation machinery dominantly regulate p53 tumor suppressor protein stability, localization, and functions in both normal and cancerous cells. Selective E3 ubiquitin ligases dominantly regulate protein levels and activities of p53 in a large range of phy...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Sane, Sanam, Rezvani, Khosrow
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343976/
https://ncbi.nlm.nih.gov/pubmed/28218667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020442
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