Proteomic Analysis of Mitochondria-Enriched Fraction Isolated from the Frontal Cortex and Hippocampus of Apolipoprotein E Knockout Mice Treated with Alda-1, an Activator of Mitochondrial Aldehyde Dehydrogenase (ALDH2)

The role of different genotypes of apolipoprotein E (apoE) in the etiology of Alzheimer’s disease is widely recognized. It has been shown that altered functioning of apoE may promote 4-hydroxynonenal modification of mitochondrial proteins, which may result in mitochondrial dysfunction, aggravation o...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Int J Mol Sci
Main Authors: Stachowicz, Aneta, Olszanecki, Rafał, Suski, Maciej, Głombik, Katarzyna, Basta-Kaim, Agnieszka, Adamek, Dariusz, Korbut, Ryszard
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343969/
https://ncbi.nlm.nih.gov/pubmed/28218653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020435
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