Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice

Obesity and its related metabolic abnormalities, including enhanced oxidative stress and chronic inflammation, are closely related to colorectal tumorigenesis. Pentoxifylline (PTX), a methylxanthine derivative, has been reported to suppress the production of tumor necrosis factor (TNF)-α and possess...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Fukuta, Kazufumi, Shirakami, Yohei, Maruta, Akinori, Obara, Koki, Iritani, Soichi, Nakamura, Nobuhiko, Kochi, Takahiro, Kubota, Masaya, Sakai, Hiroyasu, Tanaka, Takuji, Shimizu, Masahito
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343947/
https://ncbi.nlm.nih.gov/pubmed/28212276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020413
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