Preventive Effects of Pentoxifylline on the Development of Colonic Premalignant Lesions in Obese and Diabetic Mice

Obesity and its related metabolic abnormalities, including enhanced oxidative stress and chronic inflammation, are closely related to colorectal tumorigenesis. Pentoxifylline (PTX), a methylxanthine derivative, has been reported to suppress the production of tumor necrosis factor (TNF)-α and possess...

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Publicado en:Int J Mol Sci
Autores principales: Fukuta, Kazufumi, Shirakami, Yohei, Maruta, Akinori, Obara, Koki, Iritani, Soichi, Nakamura, Nobuhiko, Kochi, Takahiro, Kubota, Masaya, Sakai, Hiroyasu, Tanaka, Takuji, Shimizu, Masahito
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343947/
https://ncbi.nlm.nih.gov/pubmed/28212276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020413
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