A Plant Proteinase Inhibitor from Enterolobium contortisiliquum Attenuates Pulmonary Mechanics, Inflammation and Remodeling Induced by Elastase in Mice

Proteinase inhibitors have been associated with anti-inflammatory and antioxidant activities and may represent a potential therapeutic treatment for emphysema. Our aim was to evaluate the effects of a plant Kunitz proteinase inhibitor, Enterolobium contortisiliquum trypsin inhibitor (EcTI), on sever...

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Publicado en:Int J Mol Sci
Main Authors: Theodoro-Júnior, Osmar Aparecido, Righetti, Renato Fraga, Almeida-Reis, Rafael, Martins-Oliveira, Bruno Tadeu, Oliva, Leandro Vilela, Prado, Carla Máximo, Saraiva-Romanholo, Beatriz Mangueira, Leick, Edna Aparecida, Pinheiro, Nathalia Montouro, Lobo, Yara Aparecida, Martins, Mílton de Arruda, Oliva, Maria Luiza Vilela, Tibério, Iolanda de Fátima Lopes Calvo
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343937/
https://ncbi.nlm.nih.gov/pubmed/28216579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020403
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