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Crystal Structures of a Plant Trypsin Inhibitor from Enterolobium contortisiliquum (EcTI) and of Its Complex with Bovine Trypsin

A serine protease inhibitor from Enterolobium contortisiliquum (EcTI) belongs to the Kunitz family of plant inhibitors, common in plant seeds. It was shown that EcTI inhibits the invasion of gastric cancer cells through alterations in integrin-dependent cell signaling pathway. We determined high-res...

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Detalhes bibliográficos
Main Authors: Zhou, Dongwen, Lobo, Yara A., Batista, Isabel F. C., Marques-Porto, Rafael, Gustchina, Alla, Oliva, Maria L. V., Wlodawer, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3633903/
https://ncbi.nlm.nih.gov/pubmed/23626794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0062252
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