Phenylarsine Oxide Can Induce the Arsenite-Resistance Mutant PML Protein Solubility Changes

Arsenic trioxide (As(2)O(3)) has recently become one of the most effective drugs for treatment of patient with acute promyelocytic leukemia (APL), and its molecular mechanism has also been largely investigated. However, it has been reported that As(2)O(3) resistant patients are frequently found in r...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Jiang, Yu Han, Chen, Ye Jia, Wang, Chao, Lan, Yong Fei, Yang, Chang, Wang, Qian Qian, Hussain, Liaqat, Maimaitiying, Yasen, Islam, Khairul, Naranmandura, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343784/
https://ncbi.nlm.nih.gov/pubmed/28125064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms18020247
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