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Human fetal to adult hemoglobin switching: changes in chromatin structure of the beta-globin gene locus.

We have investigated the chromatin structure of the chromosomal DNA regions containing the human G gamma-, A gamma-, delta-, and beta-globin structural genes in both fetal and adult erythropoietic tissues and in two human erythroleukemia cells lines before and after induction. Our results indicate t...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Groudine, M, Kohwi-Shigematsu, T, Gelinas, R, Stamatoyannopoulos, G, Papayannopoulou, T
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 1983
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC534378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6200877/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.80.24.7551
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