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Chiral determination of 3,4-methylenedioxypyrovalerone enantiomers in rat serum

The emerging stimulant drug of abuse (3,4)-methylenedioxypyrovalerone [(R,S)-MDPV] is self-administered as a racemic mixture by intranasal, iv, oral, and smoking routes. The individual enantiomers are known to have widely different pharmacological effects, with (S)-MDPV showing much greater potency...

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Publicat a:Anal Methods
Autors principals: Hambuchen, Michael D., Hendrickson, Howard P., Owens, S. Michael
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343766/
https://ncbi.nlm.nih.gov/pubmed/28286575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C6AY03176E
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