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Chiral enantioresolution of cathinone derivatives present in “legal highs”, and enantioselectivity evaluation on cytotoxicity of 3,4-methylenedioxypyrovalerone (MDPV)

Recently, great interest has been focused on synthetic cathinones since their consumption has increased exponentially. All synthetic cathinones exist as chiral molecules; the biological and/or toxicological properties of cathinones generally differ according to the enantiomers in human body. In this...

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Bibliographic Details
Published in:Forensic Toxicol
Main Authors: Silva, Bárbara, Fernandes, Carla, Tiritan, Maria Elizabeth, Pinto, Madalena M.M., Valente, Maria João, Carvalho, Márcia, de Pinho, Paula Guedes, Remião, Fernando
Format: Artigo
Language:Inglês
Published: Springer Japan 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4988346/
https://ncbi.nlm.nih.gov/pubmed/27594923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11419-016-0324-y
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