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Eplerenone repolarizes muscle membrane through Na,K-ATPase activation by Tyr10 dephosphorylation
Eplerenone, an aldosterone antagonist, repolarizes muscle membrane in-vitro and increases strength in-vivo in channelopathies. In Duchenne dystrophy, it is administered for cardiomyopathy. We studied its mechanism of action on skeletal muscle to test its suitability for increasing strength in Duchen...
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| 出版年: | Acta Myol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Pacini Editore SRL
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343744/ https://ncbi.nlm.nih.gov/pubmed/28344437 |
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