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Rationale for treating oedema in Duchenne muscular dystrophy with eplerenone

Recently we reported a cytoplasmic sodium overload to cause a severe osmotic oedema in Duchenne muscular dystrophy (DMD). Our results suggested that this dual overload of sodium ions and water precedes the dystrophic process and persists until fatty muscle degeneration is complete. The present paper...

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Main Authors: LEHMANN-HORN, FRANK, WEBER, MARC-ANDRÉ, NAGEL, ARMIN M., MEINCK, HANS-MICHAEL, BREITENBACH, SIMON, SCHARRER, JOHANNES, JURKAT-ROTT, KARIN
格式: Artigo
語言:Inglês
出版: Pacini Editore SpA 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3440802/
https://ncbi.nlm.nih.gov/pubmed/22655515
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