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A canine model of human alpha-L-iduronidase deficiency.

A disease discovered in three Plott Hound littermates was found to be associated with a profound and specific deficiency of alpha-L-iduronidase (mucopolysaccharide alpha-L-iduronohydrolase; EC 3.2.1.76) in fibroblasts and leukocytes. The pedigree was consistent with autosomal recessive inheritance....

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Autors principals: Spellacy, E, Shull, R M, Constantopoulos, G, Neufeld, E F
Format: Artigo
Idioma:Inglês
Publicat: 1983
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC534366/
https://ncbi.nlm.nih.gov/pubmed/6412235
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