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Leishmania (Leishmania) amazonensis induces macrophage miR-294 and miR-721 expression and modulates infection by targeting NOS2 and L-arginine metabolism

Leishmania (Leishmania) amazonensis is an intracellular protozoan parasite responsible for the cutaneous leishmaniasis. The parasite replicates inside mammalian macrophage to establish infection. Host-pathogen interactions result in microRNA-mediated post-transcriptional regulation of host genes inv...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Muxel, Sandra Marcia, Laranjeira-Silva, Maria Fernanda, Zampieri, Ricardo Andrade, Floeter-Winter, Lucile Maria
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343489/
https://ncbi.nlm.nih.gov/pubmed/28276497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44141
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