The SWI/SNF chromatin remodelling complex is required for maintenance of lineage specific enhancers

Genes encoding subunits of SWI/SNF (BAF) chromatin remodelling complexes are collectively altered in over 20% of human malignancies, but the mechanisms by which these complexes alter chromatin to modulate transcription and cell fate are poorly understood. Utilizing mouse embryonic fibroblast and can...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Alver, Burak H., Kim, Kimberly H., Lu, Ping, Wang, Xiaofeng, Manchester, Haley E., Wang, Weishan, Haswell, Jeffrey R., Park, Peter J., Roberts, Charles W. M.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343482/
https://ncbi.nlm.nih.gov/pubmed/28262751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms14648
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