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B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers
The key signature of cancer genomes is the accumulation of DNA mutations, the most abundant of which is the cytosine-to-thymine (C-to-T) transition that results from cytosine deamination. Analysis of The Cancer Genome Atlas (TCGA) database has demonstrated that this transition is caused mainly by up...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343453/ https://ncbi.nlm.nih.gov/pubmed/28276478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep44089 |
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