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Genetic variation in the genome-wide predicted estrogen response element-related sequences is associated with breast cancer development
INTRODUCTION: Estrogen forms a complex with the estrogen receptor (ER) that binds to estrogen response elements (EREs) in the promoter region of estrogen-responsive genes, regulates their transcription, and consequently mediates physiological or tumorigenic effects. Thus, sequence variants in EREs h...
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Main Authors: | , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3109581/ https://ncbi.nlm.nih.gov/pubmed/21281495 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2821 |
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