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A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides
The apical sodium--dependent bile acid transporter (ASBT) is the main transporter to promote re-absorption of bile acids from the intestinal tract into the enterohepatic circulation. Inhibition of ASBT could increase the excretion of bile acids, thus increasing bile acid synthesis and consequently c...
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Pubblicato in: | Acta Pharm Sin B |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
Elsevier
2017
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5343113/ https://ncbi.nlm.nih.gov/pubmed/28303230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.apsb.2016.11.005 |
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