Murine Cytomegalovirus Disrupts Splenic Dendritic Cell Subsets via Type I Interferon-Dependent and -Independent Mechanisms

Dendritic cells (DC) are well-known modulators of immunity. This heterogeneous population is composed of defined subsets that exhibit functional specialization and are critical in initiating responses to pathogens. As such, many infectious agents employ strategies to disrupt DC functioning in attemp...

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Veröffentlicht in:Front Immunol
Hauptverfasser: Nash, William T., Gillespie, Alyssa L., Brown, Michael G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2017
Schlagworte:
Immunology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5343017/
https://ncbi.nlm.nih.gov/pubmed/28337202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00251
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