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Genetically determined resistance to lethal murine cytomegalovirus infection is mediated by interferon-dependent and -independent restriction of virus replication.

Susceptibility of 4-week-old mice of different strains to lethal murine cytomegalovirus (MCMV) infection was studied. Strains homozygous for H-2k and C57BL strains were resistant to greater than or equal to 10(5.5) PFU. B10.BR mice congenic for C57BL background genes and H-2k were about 10-fold more...

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Detalles Bibliográficos
Main Authors: Quinnan, G V, Manischewitz, J F
Formato: Artigo
Idioma:Inglês
Publicado: 1987
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC254193/
https://ncbi.nlm.nih.gov/pubmed/3033318
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