Cargando...
Improved glycaemia in high-fat fed neprilysin-deficient mice is associated with reduced DPP-4 activity and increased active GLP-1 levels
AIM/HYPOTHESIS: Neprilysin, a widely expressed peptidase, is upregulated in metabolically altered states such as obesity and type 2 diabetes. Like dipeptidyl peptidase-4 (DPP-4), neprilysin can degrade and inactivate the insulinotropic peptide glucagon-like peptide-1 (GLP-1). Thus, we investigated w...
Gardado en:
| Publicado en: | Diabetologia |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2016
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342915/ https://ncbi.nlm.nih.gov/pubmed/27933334 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-016-4172-4 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|