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Neprilysin Deficiency Is Associated With Expansion of Islet β-Cell Mass in High Fat-Fed Mice

Neprilysin (NEP) is an endopeptidase known to modulate nervous, cardiovascular, and immune systems via inactivation of regulatory peptides. In addition, it may also contribute to impaired glucose homeostasis as observed in type 2 diabetes (T2D). Specifically, we and others have shown that NEP is upr...

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Bibliographische Detailangaben
Veröffentlicht in:J Histochem Cytochem
Hauptverfasser: Parilla, Jacqueline H., Hull, Rebecca L., Zraika, Sakeneh
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055259/
https://ncbi.nlm.nih.gov/pubmed/29553871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1369/0022155418765164
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