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Dynamic lipopolysaccharide transfer cascade to TLR4/MD2 complex via LBP and CD14
Toll-like receptor 4 (TLR4) together with MD2, one of the key pattern recognition receptors for a pathogen-associated molecular pattern, activates innate immunity by recognizing lipopolysaccharide (LPS) of Gram-negative bacteria. Although LBP and CD14 catalyze LPS transfer to the TLR4/MD2 complex, t...
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Publicado no: | BMB Rep |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Korean Society for Biochemistry and Molecular Biology
2017
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342866/ https://ncbi.nlm.nih.gov/pubmed/28115037 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5483/BMBRep.2017.50.2.011 |
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