Soluble CD83 Inhibits T Cell Activation by Binding to the TLR4/MD-2 Complex on CD14(+) Monocytes

The transmembrane protein CD83, expressed on APCs, B cells, and T cells, can be expressed as a soluble form generated by alternative splice variants and/or by shedding. Soluble CD83 (sCD83) was shown to be involved in negatively regulating the immune response. sCD83 inhibits T cell proliferation in...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Horvatinovich, Joe M., Grogan, Elizabeth W., Norris, Marcus, Steinkasserer, Alexander, Lemos, Henrique, Mellor, Andrew L., Tcherepanova, Irina Y., Nicolette, Charles A., DeBenedette, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2017
Assuntos:
Immune Regulation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337811/
https://ncbi.nlm.nih.gov/pubmed/28193829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600802
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