p53 increase mitochondrial copy number via up-regulation of mitochondrial transcription factor A in colorectal cancer

In colorectal cancer, no study has been carried out discovering the relationship among p53, mitochondrial transcription factor A (TFAM) expression and change of mitochondrial DNA (mtDNA) copy number. In our study, co-expression of p53 and TFAM was observed in colon adenocarcinoma tissues, paracancer...

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Dettagli Bibliografici
Pubblicato in:Oncotarget
Autori principali: Wen, Shilei, Gao, Jinhang, Zhang, Linhao, Zhou, Hongying, Fang, Dingzhi, Feng, Shi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2016
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342792/
https://ncbi.nlm.nih.gov/pubmed/27732955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12514
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