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MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53
MDM2, a ubiquitin ligase, suppresses wild type TP53 via proteasome-mediated degradation. We evaluated the prognostic and therapeutic value of MDM2 in ovarian clear cell carcinoma. MDM2 expression in ovarian cancer tissues was analyzed by microarray and real-time PCR, and its relationship with progno...
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| Publicado no: | Oncotarget |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Impact Journals LLC
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342744/ https://ncbi.nlm.nih.gov/pubmed/27659536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12175 |
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