MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas

Salivary duct carcinoma (SDC) is an aggressive adenocarcinoma of the salivary glands associated with poor clinical outcome. SDCs are known to carry TP53 mutations in about 50%, however, only little is known about alternative pathogenic mechanisms within the p53 regulatory network. Particularly, data...

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Udgivet i:Oncotarget
Main Authors: Grünewald, Inga, Trautmann, Marcel, Busch, Alina, Bauer, Larissa, Huss, Sebastian, Schweinshaupt, Petra, Vollbrecht, Claudia, Odenthal, Margarete, Quaas, Alexander, Büttner, Reinhard, Meyer, Moritz F., Beutner, Dirk, Hüttenbrink, Karl-Bernd, Wardelmann, Eva, Stenner, Markus, Hartmann, Wolfgang
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342738/
https://ncbi.nlm.nih.gov/pubmed/27662657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12127
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