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MDM2 and CDK4 amplifications are rare events in salivary duct carcinomas

Salivary duct carcinoma (SDC) is an aggressive adenocarcinoma of the salivary glands associated with poor clinical outcome. SDCs are known to carry TP53 mutations in about 50%, however, only little is known about alternative pathogenic mechanisms within the p53 regulatory network. Particularly, data...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Grünewald, Inga, Trautmann, Marcel, Busch, Alina, Bauer, Larissa, Huss, Sebastian, Schweinshaupt, Petra, Vollbrecht, Claudia, Odenthal, Margarete, Quaas, Alexander, Büttner, Reinhard, Meyer, Moritz F., Beutner, Dirk, Hüttenbrink, Karl-Bernd, Wardelmann, Eva, Stenner, Markus, Hartmann, Wolfgang
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342738/
https://ncbi.nlm.nih.gov/pubmed/27662657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12127
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