Kinetics, prognostic and predictive values of ESR1 circulating mutations in metastatic breast cancer patients progressing on aromatase inhibitor

PURPOSE: To assess the prognostic and predictive value of circulating ESR1 mutation and its kinetics before and after progression on aromatase inhibitor (AI) treatment. PATIENTS AND METHODS: ESR1 circulating D538G and Y537S/N/C mutations were retrospectively analyzed by digital droplet PCR after fir...

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Vydáno v:Oncotarget
Hlavní autoři: Clatot, Florian, Perdrix, Anne, Augusto, Laetitia, Beaussire, Ludivine, Delacour, Julien, Calbrix, Céline, Sefrioui, David, Viailly, Pierre-Julien, Bubenheim, Michael, Moldovan, Cristian, Alexandru, Cristina, Tennevet, Isabelle, Rigal, Olivier, Guillemet, Cécile, Leheurteur, Marianne, Gouérant, Sophie, Petrau, Camille, Théry, Jean-Christophe, Picquenot, Jean-Michel, Veyret, Corinne, Frébourg, Thierry, Jardin, Fabrice, Sarafan-Vasseur, Nasrin, Di Fiore, Frédéric
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
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Priority Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342678/
https://ncbi.nlm.nih.gov/pubmed/27801670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12950
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