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Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo
Scopoletin is an active coumarin possessing a variety of pharmacological activities, including anti-hyperuricemic effect, but with poor solubility. To improve its oral bioavailability, we attempted to encapsulate scopoletin into Soluplus micelles (Soluplus-based scopoletin micelles, Sco-Ms) and eval...
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| Gepubliceerd in: | Acta Pharmacol Sin |
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| Hoofdauteurs: | , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342662/ https://ncbi.nlm.nih.gov/pubmed/28112183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.126 |
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