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Soluplus micelles for improving the oral bioavailability of scopoletin and their hypouricemic effect in vivo

Scopoletin is an active coumarin possessing a variety of pharmacological activities, including anti-hyperuricemic effect, but with poor solubility. To improve its oral bioavailability, we attempted to encapsulate scopoletin into Soluplus micelles (Soluplus-based scopoletin micelles, Sco-Ms) and eval...

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Bibliografiska uppgifter
I publikationen:Acta Pharmacol Sin
Huvudupphovsmän: Zeng, Ying-chun, Li, Sha, Liu, Chang, Gong, Tao, Sun, Xun, Fu, Yao, Zhang, Zhi-rong
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342662/
https://ncbi.nlm.nih.gov/pubmed/28112183
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2016.126
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