Glutathione-mediated antioxidant response and aerobic metabolism: two crucial factors involved in determining the multi-drug resistance of high-risk neuroblastoma

Neuroblastoma, a paediatric malignant tumor, is initially sensitive to etoposide, a drug to which many patients develop chemoresistance. In order to investigate the molecular mechanisms responsible for etoposide chemoresistance, HTLA-230, a human MYCN-amplified neuroblastoma cell line, was chronical...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Colla, Renata, Izzotti, Alberto, De Ciucis, Chiara, Fenoglio, Daniela, Ravera, Silvia, Speciale, Andrea, Ricciarelli, Roberta, Furfaro, Anna Lisa, Pulliero, Alessandra, Passalacqua, Mario, Traverso, Nicola, Pronzato, Maria Adelaide, Domenicotti, Cinzia, Marengo, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342585/
https://ncbi.nlm.nih.gov/pubmed/27683112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12209
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