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Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma

Multiple Myeloma (MM) is a haematological neoplasm characterised by the clonal proliferation of malignant plasma cells in the bone marrow. The success of proteasome inhibitors in the treatment of MM has highlighted the importance of the ubiquitin proteasome system (UPS) in the pathogenesis of this d...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Crawford, Lisa J., Anderson, Gordon, Johnston, Cliona K., Irvine, Alexandra E.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342567/
https://ncbi.nlm.nih.gov/pubmed/27655696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12026
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