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Identification of the APC/C co-factor FZR1 as a novel therapeutic target for multiple myeloma
Multiple Myeloma (MM) is a haematological neoplasm characterised by the clonal proliferation of malignant plasma cells in the bone marrow. The success of proteasome inhibitors in the treatment of MM has highlighted the importance of the ubiquitin proteasome system (UPS) in the pathogenesis of this d...
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Publicado no: | Oncotarget |
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Main Authors: | , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Impact Journals LLC
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5342567/ https://ncbi.nlm.nih.gov/pubmed/27655696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12026 |
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