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Preclinical investigation of ibrutinib, a Bruton's kinase tyrosine (Btk) inhibitor, in suppressing glioma tumorigenesis and stem cell phenotypes

Standard interventions for glioma include surgery, radiation and chemotherapies but the prognosis for malignant cases such as glioblastoma multiforme remain grim. Even with targeted therapeutic agent, bevacitumab, malignant glioma often develops resistance and recurrence. Thus, developing alternativ...

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שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Wei, Li, Su, Yu-Kai, Lin, Chien-Min, Chao, Tsu-Yi, Huang, Shang-Pen, Huynh, Thanh-Tuan, Jan, Hsun-Jin, Whang-Peng, Jacqueline, Chiou, Jeng-Fong, Wu, Alexander T.H., Hsiao, Michael
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2016
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342527/
https://ncbi.nlm.nih.gov/pubmed/27564106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11572
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