Bruton's tyrosine kinase (Btk) inhibitor ibrutinib suppresses stem-like traits in ovarian cancer

According to a Prognoscan database, upregulation of Bruton's tyrosine kinase (Btk) is associated with low overall survival in ovarian cancer patients. We found that spheroids-forming ovarian cancer cell, which highly expressed cancer stem-like cell (CSC) markers and Btk, were cisplatin resistan...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Zucha, Muhammad Ary, Wu, Alexander T.H., Lee, Wei-Hwa, Wang, Liang-Shun, Lin, Wan-Wan, Yuan, Chiou-Chung, Yeh, Chi-Tai
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537012/
https://ncbi.nlm.nih.gov/pubmed/26036311
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