The pathophysiological significance of PPM1D and therapeutic targeting of PPM1D-mediated signaling by GSK2830371 in mantle cell lymphoma

PPM1D is a serine/threonine phosphatase that negatively regulates key DNA damage response proteins, such as p53, p38 MAPK, histone H2A.X, and ATM. We investigated the pathophysiological significance of PPM1D and its therapeutic targeting by the novel PPM1D inhibitor GSK2830371 in mantle cell lymphom...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Kojima, Kensuke, Maeda, Aya, Yoshimura, Mariko, Nishida, Yuki, Kimura, Shinya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342503/
https://ncbi.nlm.nih.gov/pubmed/27626308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11904
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items