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Epigenome-wide association study of smoking and DNA methylation in non-small cell lung neoplasms

Tobacco smoke is a well-established lung cancer carcinogen. We hypothesize that epigenetic processes underlie carcinogenesis. The objective of this study is to examine the effects of smoke exposure on DNA methylation to search for novel susceptibility loci. We obtained epigenome-wide DNA methylation...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Freeman, Joshua R, Chu, Su, Hsu, Thomas, Huang, Yen-Tsung
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342499/
https://ncbi.nlm.nih.gov/pubmed/27602958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.11831
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