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Nitric oxide, PKC-ε, and connexin43 are crucial for ischemic preconditioning-induced chemical gap junction uncoupling

Ischemic preconditioning (IPC) maintains connexin43 (Cx43) phosphorylation and reduces chemical gap junction (GJ) coupling in cardiomyocytes to protect against ischemic damage. However, the signal transduction pathways underlying these effects are not fully understood. Here, we investigated whether...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Rong, Bing, Xie, Fei, Sun, Tao, Hao, Li, Lin, Ming-Jie, Zhong, Jing-Quan
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5342474/
https://ncbi.nlm.nih.gov/pubmed/27655723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12087
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